Lion’s Mane - properties, uses, and side effects

Lion’s Mane  -  properties, uses, and side effects
Justyna Kąkol

Justyna Kąkol

Publication: 18-06-2025

One of the most interesting medicinal and culinary mushrooms found in countries of Eastern Asia is lion’s mane (Hericium erinaceus). Thanks to its properties and complex effects, for many years it’s becoming more and more interesting to scientists. It contains many valuable elements that may support proper functioning of the nervous system, strengthen immunity and lower cholesterol levels.

How does lion’s mane work and when is it helpful? In which medical cases can it be used? Learn more about this extraordinary mushroom that’s used in traditional chinese medicine for thousands of years.

Lion’s mane - what is it?

Hericium erinaceus is a species of edible mushroom appearing mostly in deciduous forests in Asian countries like Japan or China. A bit less often it can be found in Europe, where it’s been proclaimed as endangered species. Lion’s mane is cultivated all around the world even though it’s way less popular than shiitake, white champignons or oyster mushrooms. In Poland this species is under strict control - it’s forbidden to collect these mushrooms in wilderness areas. But it can be grown at home, and it’s also possible to buy the extract in the form of ready diet supplements.

For over centuries, lion’s mane has been used in natural medicine. It takes the shape of spherical fruits covered in strings similar to icicles. It grows to 30 centimeters. It’s more often met on oak and beech tree trunks, and sometimes also on walnut and apple trees.

Lion’s mane, also known as Yamabushitake or Hou Tou Gu is perceived as a good source of nutrients. Because of numerous precious active elements, it’s been said that it has a big potential for curing many diseases, including neurological disorders, multiple sclerosis or Parkinson. In addition among properties of lion’s mane there are included focus improvement, better immunity and shorter wound healing process.

Lion’s mane - ingredients

What makes Hericium erinaceus so popular among scientists and natural medicine enthusiasts? As research shows, its secret is all in ingredients. This mushroom stands out with numerous beneficial active substances preventing inflammation, diabetes, and oxidation. Lion's mane also has immunomodulatory and anticancer properties.

The most important compounds found in hedgehog mushroom include:

  • amino acids
  • antioxidants
  • flavonoids
  • sterols
  • alkaloids
  • fatty acids
  • minerals (including phosphorus, selenium, zinc, potassium)

What’s more, the mushroom contains hericenones and erinacines - substances stimulating the synthesis of nerve growth factor NGF, indole compounds, and glycoproteins. Polysaccharides are also valuable components found in lion's mane mushrooms. Lion's Mane produces various types of polysaccharides that have a beneficial effect on digestion and intestinal health, strengthen the immune system, and help protect against disease.

Due to its high nutritional value and delicate taste, hedgehog mushroom can be successfully used as a meat substitute in a vegetarian diet. It goes perfectly with salads, pasta, and sandwiches, naturally supporting digestive health.

Lion’s mane - anticancer and health properties

Due to its pro-health properties, lion’s mane for many years has been in the interest of herbalists and dieteticians. Newest research shows that Hericium erinaceus can support proper functioning of the nervous system with neuroprotective properties. Because of that it can be used as a support in cognitive impairment therapy or slowing down the progression of neurodegenerative diseases such as Alzheimer's disease or multiple sclerosis.

Plus, active elements in lion’s mane can work positively on cognitive functions, supporting brain function and improving learning and remembering processes. The research results suggest that lion’s mane can also reduce neuron damage and decrease memory disorders’ symptoms.

Lion’s mane is also a valuable source of polysaccharides with anti-inflammating features. The polysaccharides found in the mushroom are thought to have anticancer properties, potentially assisting in the treatment of various cancers. Additionally, Lion’s Mane exhibits antioxidant qualities, helping to neutralize free radicals and reactive oxygen species, which can lower oxidative stress and slow down aging processes.

Even more impressive, Lion’s Mane may help improve fat metabolism, lower blood sugar levels, and stabilize triglyceride levels, thus reducing the risk of cardiovascular diseases.

This mushroom is also rich in essential minerals like potassium and magnesium, which are vital for nerve function, blood pressure regulation, and maintaining electrolyte balance.

Scientific research on lion’s mane

Lion’s Mane is a natural product that continues to be the subject of increasing scientific research. Studies published in prestigious journals such as Frontiers in Aging Neuroscience and International Journal of Molecular Sciences suggest that this mushroom may be useful in treating a variety of conditions.

Researchers like Chen YW, Chen WP, and Chen CC have highlighted its potential in the treatment of neurodegenerative diseases, such as Alzheimer's and Parkinson's disease. There are also studies showing that Lion’s Mane may be beneficial for gastrointestinal disorders, particularly stomach ulcers, inflammatory bowel disease, and stomach cancer.

How to use lion’s mane

In Asian culture, Lion’s Mane is often added to various dishes due to its mild, slightly nutty flavor. It’s commonly used in soups, stir-fries, or even consumed raw. Sometimes, it is steeped in hot water to make a drink, which is especially popular for individuals looking for a natural energy boost.

Lion’s Mane can be consumed in various forms, not just as a fresh mushroom but also in powdered form or as a dietary supplement. It is safe for individuals of all ages, including children and the elderly.

Soplówka jeżowata grzybnia na drzewie

Dosage of lion’s mane

Research studies have used dosages ranging from 500 mg to 3000 mg of Lion’s Mane extract, which have been shown to be safe and well-tolerated by the human body. It is recommended that consumers do not exceed 3000 mg of extract per day. Always consult the product packaging before starting supplementation and avoid exceeding the recommended daily dose.

The best time to take Lion's Mane is typically in the morning with a meal. The daily dose can also be split into two smaller servings, such as one in the morning and another during lunch.

For optimal results, consistency is key. Research suggests that the beneficial effects of Lion’s Mane can be observed after about 4 weeks of regular use.

What is the best lion’s mane supplement?

When looking for the best Lion’s Mane supplement, opt for products that contain the extract of the mushroom rather than the powdered form of the whole mushroom. Additionally, it’s a good idea to choose standardized products, which provide a specific, well-defined amount of active compounds. Most Lion’s Mane supplements are standardized for polysaccharide content.

Side effects of lion’s mane

Side effects associated with Lion’s Mane are rare and usually occur due to excessive intake of the supplement. The most common side effects are gastrointestinal, including stomach pain, nausea, vomiting, and acid reflux.

People who are allergic to mushrooms may experience allergic reactions, such as itching, skin rashes, or breathing difficulties, when taking Lion’s Mane supplements.

Contraindications for using lion’s mane

While Lion’s Mane is generally considered safe, there are some precautions to be aware of. Individuals who are allergic to mushrooms or prone to such allergies should avoid it. Additionally, it is not recommended for patients who are about to undergo surgery.

Due to the lack of sufficient research on the safety of supplementation during pregnancy and breastfeeding, women in these conditions should use Lion’s Mane with caution. Always monitor how your body reacts after the first few doses.

Everything you need to know about Hericium Erinaceus: Summary

Lion’s Mane is an exceptional mushroom that combines great taste with potential health benefits. Packed with active ingredients like polysaccharides, flavonoids, amino acids, and minerals, it can support immune function, improve concentration, lower cholesterol levels, and promote mental well-being.

As interest in natural health boosters grows, Lion’s Mane stands out as a true gem. Whether you are dealing with cognitive issues or simply want to enhance brain health and overall well-being, this mushroom might be the perfect addition to your diet.

Bibliography:

  1. https://pubmed.ncbi.nlm.nih.gov/38289992/
  2. https://pubmed.ncbi.nlm.nih.gov/26244378/
  3. https://pubmed.ncbi.nlm.nih.gov/23735479/
  4. https://pubmed.ncbi.nlm.nih.gov/38004235/
  5. https://pubmed.ncbi.nlm.nih.gov/37958943/
  6. https://pubmed.ncbi.nlm.nih.gov/23510212/
Justyna Kąkol

Justyna Kąkol

Master of European Studies

Graduate of licentiate studies in Polish philology at the University of Rzeszow and master studies in European studies at the University of Warsaw. For more than 10 years she has been creating substantive content from the scope of health, dietetics and medicine. Passionate about a healthy lifestyle, physical activity and a rational approach to diet. In her free time, she is most likely to prepare tasty, nutritious food and spend time with her family.

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